Generic Name: Pregabalin









Lyrica® (LEER-a-ka) is approved as add-on therapy in the treatment of partial onset seizures in adults.

Forms of the Medicine

Lyrica is available in capsules in eight dosage strengths from 25mg to 300mg.


Lyrica® is given by mouth. It is given two or three times per day with or without food.

Side Effects

The most common side effects include dizziness, blurred vision, weight gain, sleepiness, difficulty concentrating, swelling of hands and feet, and dry mouth.

Information for Pregnant Women and Nursing Mothers

Safety in pregnancy has not been established. It is known that women taking antiepileptic drugs have higher incidence of birth defects than women who are not. Lyrica® should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Women who are taking this medication and who wish to become pregnant should discuss treatment options with their physicians before the pregnancy begins. It is not known whether this drug is passed in breast milk, but is common with most anticonvulsants.

Drug Interactions

Lyrica® is eliminated through the kidneys and is therefore unlikely to be affected by other medications. No interactions have been observed between Lyrica® and carbamazepine, valproic acid, lamotrigine, phenytoin, phenobarbital, and topiramate.

Care During Treatment With Lyrica®

You should take the medicine as prescribed by your physician. Stopping this medication suddenly can produce unwanted side effects and potentially increase seizure frequency.

Possible Contraindications to the Use of Lyrica®

A history of an allergic reaction to pregabalin or any of its components. Not everyone experiences side effects. There may be other side effects not appearing above. For a complete list, consult your doctor, nurse, or pharmacist. More detailed sources of information on side effects are the drugÕs prescribing information sheet (package insert), the PhysicianÕs Desk Reference, or pharmaceutical company that produces the drug.

Link to product information here.

©2010 Pfizer, Inc. All rights reserved. Used with Permission.